MK4MDD

Symptoms Report

Basic Information
Name Somatic symptoms
Description "Somatic symptoms are common in patients with MDD, including fatigue and lack of energy and painful physical symptoms such as headaches and back pain. According to an analysis of data from the World Health Organization, 69% of patients in primary care settings meeting the DSM-IV/ICD-10 criteria for depression presented somatic symptoms as their primary reason for seeking medical care. Somatic symptoms in depressed patients, in particular painful physical symptoms, are associated with more severe depression of longer duration and greater functional impairment, poorer clinical outcome and higher health-care costs. Furthermore, the overlap of somatic symptoms associated with depression with other medical illnesses can impact accurate diagnosis and lead to the under-recognition of depression and misdiagnosis (Vaccarino et al, 2008; PMID: 18280580)."
No. of Studies (Positive/Negative) 5 (5/0) Help

Positive relationship between Somatic symptoms and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
chronic painful physical condition Ohayon, 2004 patients only Compared with MDD subjects without chronic pain, MDD subject...... Compared with MDD subjects without chronic pain, MDD subjects with a CPPC(chronic painful physical condition) had a longer duration of depressive symptoms (7 months longer) More...
somatic symptoms Vaccarino, 2008 patients only These results demonstrate a high prevalence and association ...... These results demonstrate a high prevalence and association of somatic symptoms in patients with MDD More...

Positive relationships between Somatic symptoms and other components at different levels (count: 9) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Somatic symptoms in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Somatic symptoms and MDD (count: 0)
Negative relationships between Somatic symptoms and other components at different levels (count: 0) Help