|Description||"Somatic symptoms are common in patients with MDD, including fatigue and lack of energy and painful physical symptoms such as headaches and back pain. According to an analysis of data from the World Health Organization, 69% of patients in primary care settings meeting the DSM-IV/ICD-10 criteria for depression presented somatic symptoms as their primary reason for seeking medical care. Somatic symptoms in depressed patients, in particular painful physical symptoms, are associated with more severe depression of longer duration and greater functional impairment, poorer clinical outcome and higher health-care costs. Furthermore, the overlap of somatic symptoms associated with depression with other medical illnesses can impact accurate diagnosis and lead to the under-recognition of depression and misdiagnosis (Vaccarino et al, 2008; PMID: 18280580)."|
|No. of Studies (Positive/Negative)||5 (5/0)|
|Genetic/epigenetic locus||Protein and other molecule||Cell and molecular pathway||Neural system||Cognition and behavior||Symptoms and signs||Environment|
1. The different color of the nodes denotes the level of the nodes.
|Genetic/Epigenetic Locus||Protein and Other Molecule||Cell and Molecular Pathway||Neural System||Cognition and Behavior||Symptoms and Signs||Environment||MDD|
3. The network is generated using Cytoscape Web