Symptoms Report

Name	Fatigue
Description	Fatigue is a state of awareness describing a range of afflictions, usually associated with physical and/or mental weakness, though varying from a general state of lethargy to a specific work-induced burning sensation within one's muscles.
No. of Studies (Positive/Negative)	7 (7/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
tiredness	Serretti, 2004	patients only		The most frequently represented depressive symptoms in MDD w...... The most frequently represented depressive symptoms in MDD were Loss of energy/tiredness, Loss of pleasure, Poor concentration, and Sleep disorders. More...
excessive tiredness	Krishnakumar, 2006	patients only		Children with depressive disorder had significantly more fam...... Children with depressive disorder had significantly more family members affected with mental illnesses. The clinical features included diminished interest in play and activities, excessive tiredness, low self- esteem, problems with concentration, multiple somatic complaints, behavior symptoms like anger and aggression, recent deterioration in school performance and suicidal behavior. More...
fatigue	Ferentinos, 2009	patients only		The severity of fatigue was significantly correlated with HD...... The severity of fatigue was significantly correlated with HDRS (Hamilton Depression Rating Scale) score. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
fatigue		ventral frontal lobe(ventral frontal lobe)	brain morphology and function	Brody, 2001	patients only		Improvement in anxiety/somatization [ANX], psychomotor retar...... Improvement in anxiety/somatization [ANX], psychomotor retardation [PR], tension [TENS] and fatigue [FATIG] factors was associated with decreasing ventral frontal lobe metabolism. More...
fatigue		Alertness(alertness)	cognition and behavior	Pedrelli, 2010	patients only		Fatigue was significantly associated with inability to focus...... Fatigue was significantly associated with inability to focus, alertness, and feeling blue More...
fatigue		Attention(inability to focus)	cognition and behavior	Pedrelli, 2010	patients only		Fatigue was significantly associated with inability to focus...... Fatigue was significantly associated with inability to focus, alertness, and feeling blue More...
fatigue		Somatic symptoms(chronic painful physical condition)	symptoms	Ohayon, 2004	patients only		Compared with MDD subjects without chronic pain, MDD subject...... Compared with MDD subjects without chronic pain, MDD subjects with a CPPC(chronic painful physical condition) had a longer duration of depressive symptoms (7 months longer) and were more likely to report severe fatigue (OR = 5.4), More...
fatigue		Sleep disturbances(sleep disturbance)	symptoms	Liu, 2007	patients only		Across sleep-disturbed children, those with both insomnia an...... Across sleep-disturbed children, those with both insomnia and hypersomnia had a longer history of illness, were more severely depressed, and were more likely to have anhedonia, weight loss, psychomotor retardation, and fatigue than were those with either insomnia or hypersomnia. More...
fatigue		Sleep disturbances(sleep disturbances)	symptoms	Ferentinos, 2009	patients only		The severity of fatigue was significantly correlated with AI...... The severity of fatigue was significantly correlated with AIS (Athens Insomnia Scale) total score, awakenings during the night (AIS item 2), compromised sleep quality (AIS item 5), and ESS score. Sleep quality (AIS item 5) and daytime sleepiness (ESS) were the only significant predictors of the severity of fatigue in the multiple regression analysis. More...
fatigue		Depressed mood(feeling blue)	symptoms	Pedrelli, 2010	patients only		Fatigue was significantly associated with inability to focus...... Fatigue was significantly associated with inability to focus, alertness, and feeling blue More...

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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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