MK4MDD

Gene Report

Basic Information
Approved Symbol SIGMAR1
Approved Name sigma non-opioid intracellular receptor 1
Previous Symbol OPRS1
Previous Name "opioid receptor, sigma 1"
Symbol Alias SR-BP1
Location 9p13.3
Position chr9:34637695-34637768 (-)
External Links Entrez Gene: 10280
Ensembl: ENSG00000147955
UCSC: uc003zvb.3
HGNC ID: 8157
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin; SNP mapped

Positive relationships between SIGMAR1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
sigma 1 receptor gene (SIGMAR1) Kishi, 2010 patients and normal controls In the logistic regression analysis, we detected an associat...... In the logistic regression analysis, we detected an association of the phenotypes (MDD or controls) with rs1800866 in this gene. More...

Positive relationships between SIGMAR1 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of SIGMAR1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between SIGMAR1 and MDD (count: 0)
Negative relationships between SIGMAR1 and other components at different levels (count: 0) Help
SIGMAR1 related SNPs in MK4MDD (count: 1)
SIGMAR1 related proteins in MK4MDD (count: 0)
SIGMAR1 related GO terms (count: 17)
SIGMAR1 related KEGG pathways (count: 0)
SIGMAR1 related BioCarta pathways (count: 0)
SIGMAR1 related Reactome pathways (count: 0)
SIGMAR1 related interactors from protein-protein interaction data in HPRD (count: 2)