Molecule Report

Basic Information

Name	Phosphorylcholine
Description	Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
MeSH ID	D010767
No. of Studies (Positive/Negative)	3(3/0)

Positive relationship between Phosphorylcholine and MDD (count: 2)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
phosphocholine	Caetano, 2005	patients and normal controls		Depressed subjects had significantly lower levels of glycero...... Depressed subjects had significantly lower levels of glycerophosphocholine plus phosphocholine (GPC + PC; or choline-containing compounds) and higher myo-inositol levels in the left DLPFC compared to healthy controls. I More...
phosphocholine	Olvera, 2010	patients and normal controls		MDD subjects also had significantly lower levels of GPC+PC i...... MDD subjects also had significantly lower levels of GPC+PC in the right AC than control subjects. More...

Positive relationships between Phosphorylcholine and other components at different levels (count: 3)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Relation Description
Name in Literature	Related Components
phosphocholine		right anterior cingulate cortex(right anterior cingulate(AC))	brain morphology and function	Olvera, 2010	patients and normal controls	MDD subjects also had significantly lower levels of GPC+PC i...... MDD subjects also had significantly lower levels of GPC+PC in the right AC than control subjects. More...
phosphocholine (PCh)		Reaction time(processing speed)	cognition and behavior	Elderkin-Thompson, 2004	patients and normal controls	There was a significant difference in the overall pattern of...... There was a significant difference in the overall pattern of associations between the four metabolites (Ch, PCh, Cr, and mI) and verbal learning and processing speed in depressed patients compared to healthy controls. More...
phosphocholine (PCh)		Learning(verbal learning)	cognition and behavior	Elderkin-Thompson, 2004	patients and normal controls	There was a significant difference in the overall pattern of...... There was a significant difference in the overall pattern of associations between the four metabolites (Ch, PCh, Cr, and mI) and verbal learning and processing speed in depressed patients compared to healthy controls. More...

Positive relationship network of Phosphorylcholine in MK4MDD

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationship between Phosphorylcholine and MDD (count: 0)

Negative relationships between Phosphorylcholine and other components at different levels (count: 0)