MK4MDD

Gene Report

Basic Information
Approved Symbol NR1D1
Approved Name nuclear receptor subfamily 1, group D, member 1
Previous Symbol THRAL
Symbol Alias ear-1, hRev, Rev-ErbAalpha, THRA1
Location 17q11.2
Position chr17:38256348-38256978 (-)
External Links Entrez Gene: 9572
Ensembl: ENSG00000126368
UCSC: uc002htz.3
HGNC ID: 7962
No. of Studies (Positive/Negative) 2(1/1) Help
Type Literature-origin

Positive relationships between NR1D1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
NR1D1 Byrne EM, 2014 Patients and nomal controls P-Values=0.03 The NR1D1 gene was the only circadian gene to show nominal s...... The NR1D1 gene was the only circadian gene to show nominal significance with major depression (P?0.03).When ranking genes based on the most significant SNP, the strongest signal was rs9353523 in the CNR1 gene (P?0.001). This gene ranked in the 95th percentile when ranking genes based on their most significant P-value. More...

Positive relationships between NR1D1 and other components at different levels (count: 0) Help
Positive relationship network of NR1D1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between NR1D1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
NR1D1 Kishi T, 2008 Patients and nomal controls No significant association was found with major depressive d...... No significant association was found with major depressive disorder More...

Negative relationships between NR1D1 and other components at different levels (count: 0) Help
NR1D1 related SNPs in MK4MDD (count: 0)
NR1D1 related proteins in MK4MDD (count: 0)
NR1D1 related GO terms (count: 44)
NR1D1 related KEGG pathways (count: 1)
NR1D1 related BioCarta pathways (count: 0)
NR1D1 related Reactome pathways (count: 2)
NR1D1 related interactors from protein-protein interaction data in HPRD (count: 5)