Brain Morphology and Function Report

Name	Medial frontal gyrus
Brain Morphology	The superior frontal gyrus is situated above the superior frontal sulcus and is continued on to the medial surface of the hemisphere, the medial frontal gyrus. The portion on the lateral surface of the hemisphere is usually more or less completely subdivided into an upper and a lower part by an antero-posterior sulcus, the paramedial sulcus, which, however, is frequently interrupted by bridging gyri.
Brain Function	There is some evidence that it plays a role in executive mechanisms.
Picture	From Wiki.
No. of Studies (Positive/Negative)	5(5/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
medial frontal gyrus	Kumari, 2003	patients and normal controls		Compared with control participants, patients showed relative...... Compared with control participants, patients showed relatively decreased response in the medial frontal gyrus with positive picture-caption pairs. More...
medial frontal gyrus	Costafreda, 2009	patients and normal controls		Decreased grey matter density in the medial frontal gyrus (B...... Decreased grey matter density in the medial frontal gyrus (BA 11) showed the highest contribution to the diagnosis of depression. More...
medial frontal gyrus	Lemogne, 2009	patients and normal controls		Both patients and healthy subjects activated the MFG in 'sel...... Both patients and healthy subjects activated the MFG in 'self' vs 'general' condition. However, the activation of the dorsal part of the MFG (medial frontal gyrus) and of the dorsolateral prefrontal cortex (DLPFC) in 'self' vs 'general' condition was unique to patients. More...
medial frontal gyrus	Liu, 2010	patients and normal controls	P-value < 0.01	ReHo(regional homogeneity) in the MD group decreased in the ...... ReHo(regional homogeneity) in the MD group decreased in the left medial frontal gyrus, right medial frontal gyrus (P<0.01). More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
medial frontal gyrus		CACNA1C(CACNA1C)	gene	Thimm, 2011	normal people		Risk allele carriers showed impaired performance in alerting...... Risk allele carriers showed impaired performance in alerting and orienting in addition to reduced neural activity in the right inferior parietal lobule [Brodmann area (BA) 40] during orienting and in the medial frontal gyrus (BA 8) during executive control of attention. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web