MK4MDD

Gene Report

Basic Information
Approved Symbol MAN2A1
Approved Name mannosidase, alpha, class 2A, member 1
Previous Symbol MANA2
Symbol Alias GOLIM7
Name Alias "golgi integral membrane protein 7"
Location 5q21.3
Position chr5:109202700-109203429 (+)
External Links Entrez Gene: 4124
Ensembl: ENSG00000112893
UCSC: uc003kou.1
HGNC ID: 6824
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between MAN2A1 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
MAN2A1 Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder
MAN2A1 Sequeira A, 2009 patients and nomal controls Group: P-value=0.016, F=5; Substance: P-value=0.005, F=9.5 Genes differentially expressed after an ANCOVA analysis betw...... Genes differentially expressed after an ANCOVA analysis between the three groups(C = control, S = suicide, SMD = suicide with major depression). More...

Positive relationships between MAN2A1 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of MAN2A1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between MAN2A1 and MDD (count: 0)
Negative relationships between MAN2A1 and other components at different levels (count: 0) Help
MAN2A1 related SNPs in MK4MDD (count: 0)
MAN2A1 related proteins in MK4MDD (count: 0)
MAN2A1 related GO terms (count: 23)
MAN2A1 related KEGG pathways (count: 1)
MAN2A1 related BioCarta pathways (count: 0)
MAN2A1 related Reactome pathways (count: 0)
MAN2A1 related interactors from protein-protein interaction data in HPRD (count: 0)