Gene Report

Basic Information

Approved Symbol	JAKMIP1
Approved Name	janus kinase and microtubule interacting protein 1
Symbol Alias	MARLIN1, JAMIP1, Gababrbp, FLJ31564
Location	4p16.1
Position	chr4:6201980-6202282 (-)
External Links	Entrez Gene: 152789 Ensembl: ENSG00000152969 UCSC: uc010idb.1 HGNC ID: 26460
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between JAKMIP1 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
MARLIN1	Sequeira, 2007	patients and normal controls		Selected differentially expressed genes in hippocampus Selected differentially expressed genes in hippocampus

Positive relationships between JAKMIP1 and other components at different levels (count: 1)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
Name in Literature	Related Components
MARLIN1		Hippocampus(hippocampus)	brain morphology and function	Sequeira, 2007	patients and normal controls		Selected differentially expressed genes in hippocampus Selected differentially expressed genes in hippocampus

Positive relationship network of JAKMIP1 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between JAKMIP1 and MDD (count: 0)

Negative relationships between JAKMIP1 and other components at different levels (count: 0)

JAKMIP1 related SNPs in MK4MDD (count: 0)

JAKMIP1 related proteins in MK4MDD (count: 0)

JAKMIP1 related GO terms (count: 12)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0015031	protein transport	biological process	IEA
GO:0019898	extrinsic component of membrane	cellular component	IDA[14718537]
GO:0019900	kinase binding	molecular function	IEA
GO:0030529	intracellular ribonucleoprotein complex	cellular component	IDA[14718537]
GO:0008017	microtubule binding	molecular function	IEA
GO:0019894	kinesin binding	molecular function	IEA
GO:0005874	microtubule	cellular component	IEA
GO:0005737	cytoplasm	cellular component	IEA
GO:0050890	cognition	biological process	IMP[17519220]
GO:0003723	RNA binding	molecular function	IDA[14718537]
GO:0005515	protein binding	molecular function	IPI[17500595]
GO:0050811	GABA receptor binding	molecular function	IDA[14718537]

JAKMIP1 related KEGG pathways (count: 0)

JAKMIP1 related BioCarta pathways (count: 0)

JAKMIP1 related Reactome pathways (count: 0)

JAKMIP1 related interactors from protein-protein interaction data in HPRD (count: 5)

Gene	Interactor	Interactor in MK4MDD?	Experiment Type	PMID
JAKMIP1	JAK1	No	in vitro;in vivo	15277531
JAKMIP1	TYK2	No	in vivo;yeast 2-hybrid	15277531
JAKMIP1	YWHAG	No	in vivo	15324660
JAKMIP1	JAKMIP1	Yes	in vivo	15277531
JAKMIP1	GABBR1	Yes	in vitro	14718537

Gene Report

Gene mapped GO terms