MK4MDD

Gene Report

Basic Information
Approved Symbol IKBKE
Approved Name inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
Symbol Alias IKKE, IKK-i, KIAA0151
Location 1q31
Position chr1:206669479-206670223 (+)
External Links Entrez Gene: 9641
Ensembl: ENSG00000143466
UCSC: uc001hdz.2
HGNC ID: 14552
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between IKBKE and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
IKBKE Koido K, 2010 Patients and nomal controls Significant associations were detected for SNP rs1539243 in ...... Significant associations were detected for SNP rs1539243 in IKBKE (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon) gene showing different allelic and genotypic distributions in the total as well as in separate diagnostic groups as compared to controls. More...
IKBKE Traks T, 2015 Patients and nomal controls The presented results confirm our initial findings and indic...... The presented results confirm our initial findings and indicate a possible role of IKBKE gene in mood and anxiety disorders. Several single marker and haplotype associations were evident for both MDD and PD, although the ones concerning MDD were more convincing. More...

Positive relationships between IKBKE and other components at different levels (count: 0) Help
Positive relationship network of IKBKE in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between IKBKE and MDD (count: 0)
Negative relationships between IKBKE and other components at different levels (count: 0) Help
IKBKE related SNPs in MK4MDD (count: 0)
IKBKE related proteins in MK4MDD (count: 0)
IKBKE related GO terms (count: 32)
IKBKE related KEGG pathways (count: 3)
IKBKE related BioCarta pathways (count: 0)
IKBKE related Reactome pathways (count: 4)
IKBKE related interactors from protein-protein interaction data in HPRD (count: 12)