MK4MDD

Gene Report

Basic Information
Approved Symbol CD46
Approved Name CD46 molecule, complement regulatory protein
Previous Symbol MIC10, MCP
Previous Name antigen identified by monoclonal antibody TRA-2-10, "membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)", "CD46 antigen, complement regulatory protein"
Symbol Alias TRA2.10, MGC26544, TLX
Location 1q32
Position chr1:207925383-207968861 (+)
External Links Entrez Gene: 4179
Ensembl: ENSG00000117335
UCSC: uc001hgj.3
HGNC ID: 6953
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between CD46 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
CD46 antigen, complement regulatory protein Tochigi, 2008 patients and normal controls Genes differentially expressed in major depression Genes differentially expressed in major depression

Positive relationships between CD46 and other components at different levels (count: 0) Help
Positive relationship network of CD46 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between CD46 and MDD (count: 0)
Negative relationships between CD46 and other components at different levels (count: 0) Help
CD46 related SNPs in MK4MDD (count: 0)
CD46 related proteins in MK4MDD (count: 1)
CD46 related GO terms (count: 15)
CD46 related KEGG pathways (count: 1)
CD46 related BioCarta pathways (count: 0)
CD46 related Reactome pathways (count: 0)
CD46 related interactors from protein-protein interaction data in HPRD (count: 10)