|Citation||Kronmuller, 2008 PubMed
|Full Info||Kronmuller, K.T., Pantel, J., Kohler, S., Victor, D., Giesel, F., Magnotta, V.A., Mundt, C., Essig, M. and Schroder, J. (2008) Hippocampal volume and 2-year outcome in depression. Br J Psychiatry, 192, 472-473.
|Hypothesis or Background
Although the hippocampus has been found to be smaller in people with depression, the clinical relevance of this is unclear.
|Sample Information||57 patients with major depression |
|Method Detail||We investigated hippocampal volume (using high-resolution magnetic resonance imaging) and 2-year outcome in 57 patients with major depression.
|Method Keywords||magnetic resonance imaging (MRI)
|Result||The left and right hippocampal volumes of patients with a depression relapse were significantly smaller than those of healthy controls.
|Conclusions||Our results support the hypothesis that the hippocampus is crucial in the outcome of depression.
Relationships reported by Kronmuller, 2008