Study Report
Reference
| Citation | Kronmuller, 2008 PubMed |
| Full Info | Kronmuller, K.T., Pantel, J., Kohler, S., Victor, D., Giesel, F., Magnotta, V.A., Mundt, C., Essig, M. and Schroder, J. (2008) Hippocampal volume and 2-year outcome in depression. Br J Psychiatry, 192, 472-473.
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Study
| Hypothesis or Background |
Although the hippocampus has been found to be smaller in people with depression, the clinical relevance of this is unclear.
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| Sample Information | 57 patients with major depression |
|---|
| Method Detail | We investigated hippocampal volume (using high-resolution magnetic resonance imaging) and 2-year outcome in 57 patients with major depression. |
| Method Keywords | magnetic resonance imaging (MRI) |
| Result | The left and right hippocampal volumes of patients with a depression relapse were significantly smaller than those of healthy controls. |
| Conclusions | Our results support the hypothesis that the hippocampus is crucial in the outcome of depression. |
Relationships reported by
Kronmuller, 2008
| Component A Approved Name (Name in Paper) |
Component A Type |
Component B Approved Name (Name in Paper) |
Component B Type |
Statistical Result |
Relationship Description |
Result Category (Positive/Negative)) |
|
MDD
|
syndrome |
Hippocampus (hippocampal volumes) |
brain morphology and function |
|
The left and right hippocampal volumes of patients with a depression relapse were significantly smaller than those of healthy controls. |
Positive
|
