Study Report
Reference
| Citation | Hashimoto R, 2005 PubMed |
| Full Info | Hashimoto R, Suzuki T, Iwata N, Yamanouchi Y, Kitajima T, Kosuga A et al. Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders. J Neural Transm 2005; 112(2): 303-307
|
Study
| Hypothesis or Background |
Two research groups have recently reported a significant association between schizophrenia and genetic variants of Frizzled-3 (FZD3) gene.
|
| Sample Information | Japanese sample of schizophrenia, bipolar disorder, unipolar depression and controls |
|---|
| Method Detail | We examined a possible association in a Japanese sample of schizophrenia, bipolar disorder, unipolar depression and controls with four single nucleotide polymorphisms (SNPs), tested in previous reports. |
| Method Keywords | genotyping |
| Result | We failed to find significant association in the four SNPs or haplotype analysis. |
| Conclusions | The FZD3 gene might not play a role in conferring susceptibility to major psychosis in our sample. |
Relationships reported by
Hashimoto R, 2005
| Component A Approved Name (Name in Paper) |
Component A Type |
Component B Approved Name (Name in Paper) |
Component B Type |
Statistical Result |
Relationship Description |
Result Category (Positive/Negative)) |
|
MDD
|
syndrome |
FZD9 (FZD3) |
gene |
|
We failed to find significant association in the four SNPs or haplotype analysis |
Negative
|
