Reactome Pathway Report
Basic Information
| ID |
|
| Name |
rna polymerase_iii_transcription_initiation
|
| Description |
There are three basic types of RNA polymerase III promoters. The three types of RNA polymerase III promoters are known as type 1, type 2, and type 3 promoters. Type 1 promoters are found in the 5S genes and consist of a gene-internal element called the internal control region. Type 2 promoters are found in tRNA genes, Adenovirus 2 VAI gene, and other genes. These promoters consists of two gene-internal elements called the A and the B boxes. Type 3 promoters consist of a distal sequence element. Some promoters combine elements from type 2 and 3 promoters. For example, the S. cerevisiae U6 promoter, also shown in the figure, contains the TATA box typical of type 3 promoters and the A and B boxes typical of type 2 promoters. Moreover, in S. pombe, nearly all tRNA and 5S genes contain a TATA box in addition to gene-internal elements, and the TATA box is required for transcription.
|
REACT_281 related genes in MK4MDD (count: 1)
| Approved Symbol |
Approved Name |
Type |
No. of Studies (Positive/Negative) |
| BRF2 |
BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like |
Literature-origin
|
1(1/0) |
