Reactome Pathway Report
Basic Information
| ID |
|
| Name |
copi mediated_transport
|
| Description |
Secretory transport depends on membrane-bounded carriers to move protein and lipid between intracellular compartments. The COPI coat has a central role in this process, creating a sorting domain on the membrane into which cargo proteins, destined to return to the endoplasmic reticulum (ER), concentrate. The membrane domain deforms into a coated bud, pinches off the membrane as a coated carrier, and then uncoats. Successful operation of the COPI coat system is necessary for selective retrieval of protein and lipid components back to the ER.
|
REACT_11096 related genes in MK4MDD (count: 1)
| Approved Symbol |
Approved Name |
Type |
No. of Studies (Positive/Negative) |
| COPA |
coatomer protein complex, subunit alpha |
Literature-origin
|
1(1/0) |
