SNP Report

Name	rs821616 dbSNP Ensembl
Location	Chrchr1:232008852(Forward)
Variant Alleles	A/T
Ancestral Allele	A
No. of Studies (Positive/Negative)	2 (1/1)

Reference	Research Type	Statistical Result	Relation Description
Bosker, 2010	patients and normal controls		Significance of candidate SNPs for MDD identified from the l...... Significance of candidate SNPs for MDD identified from the literature within the GAIN MDD GWAS More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Reference	Research Type	Statistical Result	Relation Description
Arias, 2014	Patients and nomal controls	p(genotype)=0.16; p(allele)=0.09	Rs3738401 (DISC1), rs1615409 and rs766288 (TSNAX) showed gen...... Rs3738401 (DISC1), rs1615409 and rs766288 (TSNAX) showed genotypic and allelic evidence of association with the risk of MDD (Supplementary Table 2). Logistic regression models controlled for age confirmed the association of these polymorphisms with MDD (Table 1). In detail, rs3738401 AA genotype, rs1615409 AA genotype and rs766288 T allele were associated with lower MDD risk(p=0.004; p=0.0019; p=0.008, respectively). More...

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
DISC1	disrupted in schizophrenia 1	Literature-origin; SNP mapped; Protein mapped	3(3/0)