MK4MDD

SNP Report

Basic Information
Name rs6313 dbSNP Ensembl
Location Chrchr13:46895805(Forward)
Variant Alleles G/A
Ancestral Allele G
No. of Studies (Positive/Negative) 2 (1/1) Help

Positive relationship between rs6313 and MDD (count: 1)
Reference Research Type Statistical Result Relation Description Help
Bosker, 2010 patients and normal controls Significance of candidate SNPs for MDD identified from the l...... Significance of candidate SNPs for MDD identified from the literature within the GAIN MDD GWAS More...

Relationships between rs6313 and other components at different levels (count: 0) Help
Positive relationship network of rs6313 in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between rs6313 and MDD (count: 1)
Reference Research Type Statistical Result Relation Description
Tan, 2014 Patients and nomal controls allele frequency model (OR=1.006, 95% CI: 0.914¨C1.107, P=0.908); dominant genotype model (OR=0.999, 95% CI: 0.845¨C1.181, P=0.994); recessive genotype model (OR=1.033, 95% CI: 0.919¨C1.161, P=0.592); co-dominant genotypemodel 1(OR=1.022,95%CI: 0.903¨C1.158, P=0.73); co-dominant genotype model 2 (OR=1.012, 95% CI:0.891¨C1.148, P=0.856); homozygote model (OR=0.993, 95% CI: 0.807¨C1.222, P=0.949) We included 22 studies (from 1997 to 2011) thatwere made up ...... We included 22 studies (from 1997 to 2011) thatwere made up of 3,140 cases and 4,201 controls for the analysis on MDD. Based on OR and 95% CI, no significant ssociation with MDD risk was provided. The OR and 95% CI in six genetic models were: allele frequency model (OR=1.006, 95% CI: 0.914¨C1.107, P=0.908); dominant genotype model (OR=0.999, 95% CI: 0.845¨C1.181, P=0.994); recessive genotype model (OR=1.033, 95% CI: 0.919¨C1.161, P=0.592); co-dominant genotypemodel 1(OR=1.022,95%CI: 0.903¨C1.158, P=0.73); co-dominant genotype model 2 (OR=1.012, 95% CI:0.891¨C1.148, P=0.856); homozygote model (OR=0.993, 95% CI: 0.807¨C1.222, P=0.949) More...

Negative relationships between rs6313 and other components at different levels (count: 0) Help
rs6313 related genes (count: 1)