SNP Report

Name	rs6198 dbSNP Ensembl
Location	Chrchr5:143278056(Forward)
Variant Alleles	T/C
Ancestral Allele	T
No. of Studies (Positive/Negative)	2 (2/0)

Reference	Research Type	Statistical Result	Relation Description
Szczepankiewicz, 2011	patients and normal controls		We have found three polymorphisms (rs6198, rs6191 and rs3338...... We have found three polymorphisms (rs6198, rs6191 and rs33388) to be associated with major depressive disorder (MDD) More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
rs6198		rs9470080(rs9470080)	SNP	Szczepankiewicz, 2014	Patients and nomal controls	P-value=0.003	we observed that the best model of interactive variants was ...... we observed that the best model of interactive variants was found for 2-locus model (rs9470080 of FKBP5 and rs6198 of NR3C1) with testing balance accuracy of 60.4%, cross-validation consistency 10/10 (100%) and an empiric p value of 0.003 based on 1000-fold permutation test.. We also report here for the first time that interaction between two SNPs: rs9470080 of FKBP5 and rs6198 of NR3C1 may modulate depression risk. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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