MK4MDD

SNP Report

Basic Information
Name rs4680 dbSNP Ensembl
Location Chrchr22:19963748(Forward)
Variant Alleles G/A
Ancestral Allele G
No. of Studies (Positive/Negative) 4 (2/2) Help

Positive relationship between rs4680 and MDD (count: 2)
Reference Research Type Statistical Result Relation Description Help
Massat, 2005 patients and normal controls An association was found between the high-activity COMT Val ...... An association was found between the high-activity COMT Val allele, particularly the COMT Val/Val genotype and early-onset MDD. More...
Bosker, 2010 patients and normal controls Significance of candidate SNPs for MDD identified from the l...... Significance of candidate SNPs for MDD identified from the literature within the GAIN MDD GWAS More...

Relationships between rs4680 and other components at different levels (count: 0) Help
Positive relationship network of rs4680 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between rs4680 and MDD (count: 2)
Reference Research Type Statistical Result Relation Description
lli A, 2010 Patients and nomal controls We could not demonstrate any significant difference in the d...... We could not demonstrate any significant difference in the distribution of this COMT single-nucleotide polymorphism (SNP) in the treatment response to selective serotonin reuptake inhibitors or between patients with MDD and control subjects More...
Wang X, 2014 Patients and nomal controls t or ¦Ö2(allele)=1.779;p(allele)=0.182;t or ¦Ö2(Genotype)=3.768;p(Genotype)=0.052; There were no significant differences in genotype and allele...... There were no significant differences in genotype and allele frequency in MTHFR or in COMT genotype between the patients and the controls. More...

Negative relationships between rs4680 and other components at different levels (count: 0) Help
rs4680 related genes (count: 1)