MK4MDD

SNP Report

Basic Information
Name rs2522833 dbSNP Ensembl
Location Chrchr7:82824392(Forward)
Variant Alleles A/C
Ancestral Allele A
No. of Studies (Positive/Negative) 4 (4/0) Help

Positive relationship between rs2522833 and MDD (count: 3)
Reference Research Type Statistical Result Relation Description Help
Sullivan, 2009 patients and normal controls P-value=1.2E(-6) Of the top 200, 11 signals localized to a 167 kb region over...... Of the top 200, 11 signals localized to a 167 kb region overlapping the gene piccolo (PCLO, whose protein product localizes to the cytomatrix of the presynaptic active zone and is important in monoaminergic neurotransmission in the brain) with P-values of 7.7 x 10(-7) for rs2715148 and 1.2 x 10(-6) for rs2522833. More...
Hek K, 2010 Patients and nomal controls Logistic regression analysis showed an association between r...... Logistic regression analysis showed an association between rs2522833 and depressive disorders (P = 0.0025) More...
Minelli A, 2012 patients and normal controls P-value<0.01 The results showed that rs2522833 CC homozygotes were more f...... The results showed that rs2522833 CC homozygotes were more frequent among the depressed patients than in the controls (p<0.01) More...

Relationships between rs2522833 and other components at different levels (count: 3) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of rs2522833 in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between rs2522833 and MDD (count: 0)
Negative relationships between rs2522833 and other components at different levels (count: 0) Help
rs2522833 related genes (count: 1)