Brain Morphology and Function Report

Name	left frontal cortex
Brain Morphology	Please reference to the description for Frontal Lobe
No. of Studies (Positive/Negative)	6(5/1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
left anterofrontal cortical areas	Tutus, 1998	patients and normal controls		We found significant differences between the PI (perfusion i...... We found significant differences between the PI (perfusion index) values of the untreated depressed patients and those of the controls, indicating relatively reduced perfusion in the left anterofrontal and left temporal cortical areas. More...
left frontal cortex	Reivich, 2004	patients and normal controls	P-value = 0.013	Patients showed significantly larger DV (distribution volume...... Patients showed significantly larger DV (distribution volume) ratios in the left frontal cortex (P=0.013) and right cingulate cortex (P=0.043) compared to control subjects. More...
left frontal lobe	Abe, 2010	patients and normal controls		Local areas showing an increase of MD (mean diffusivity) in ...... Local areas showing an increase of MD (mean diffusivity) in depressive patients were observed in the left frontal and temporal lobes More...
left frontal cortex	Stewart, 2010	patients and normal controls		Lifetime MDD was linked to relatively less left frontal acti...... Lifetime MDD was linked to relatively less left frontal activity for both sexes using a current source density (CSD) reference. More...
left frontal region	Vreeburg, 2010	patients and normal controls		Lifetime depressed individuals displayed less relative left ...... Lifetime depressed individuals displayed less relative left frontal activity than never-depressed individuals during all facial expressions across four EEG reference montages More...

---

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
left frontal region	Bonte, 2001	patients and normal controls		Other localizations in the left frontal and bilateral prefro...... Other localizations in the left frontal and bilateral prefrontal regions did not attain significance, but each localization contained statistically significant maxima (z scores). More...