Protein Report

Protein Name	cAMP-dependent protein kinase catalytic subunit alpha
UniPortKB	P17612
No. of Studies (Positive/Negative)	3 (3/0)
Type	Literature-origin

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
PKA	Shelton, 2009	patients and normal controls		Basal and cyclic AMP-stimulated PKA activity was also reduce...... Basal and cyclic AMP-stimulated PKA activity was also reduced in the depressed sample More...
PKA catalytic alpha	Shelton, 2009	patients and normal controls		The MDD sample exhibited significantly lower protein express...... The MDD sample exhibited significantly lower protein expression of PKA regulatory Ialpha (RIalpha), PKA catalytic alpha (Calpha) and Cbeta, PKCbeta1, and PKCepsilon relative to controls. More...
cAMP-dependent protein kinase catalytic subunit a	Ditzen C, 2012	patients and normal controls		Regulated Protein in Cerebrospinal Fluid of Depressed Patien...... Regulated Protein in Cerebrospinal Fluid of Depressed Patients More...

Name in Literature	Related Components
	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
PKA		5-hydroxytryptamine receptor 2A(5-HT(2A) receptor)	protein	Shelton, 2009	patients and normal controls		5-HT(2A) receptor availability was significantly inversely c...... 5-HT(2A) receptor availability was significantly inversely correlated with PKC activity in controls, but with PKA activity in the depressed sample More...

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1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
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3. The network is generated using Cytoscape Web

Gene Symbol	Gene Name	Type	No. of Studies (Positive/Negative)	Add to Relationship Set
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	Protein mapped	0 (0/0)