MK4MDD

Protein Report

Basic Information
Protein Name cAMP-dependent protein kinase catalytic subunit alpha
UniPortKB P17612
No. of Studies (Positive/Negative) 3 (3/0) Help
Type Literature-origin
Positive relationship between cAMP-dependent protein kinase catalytic subunit alpha and MDD (count: 3)
Name in Literature Reference Research Type Statistical Result Relation Description Help
PKA Shelton, 2009 patients and normal controls Basal and cyclic AMP-stimulated PKA activity was also reduce...... Basal and cyclic AMP-stimulated PKA activity was also reduced in the depressed sample More...
PKA catalytic alpha Shelton, 2009 patients and normal controls The MDD sample exhibited significantly lower protein express...... The MDD sample exhibited significantly lower protein expression of PKA regulatory Ialpha (RIalpha), PKA catalytic alpha (Calpha) and Cbeta, PKCbeta1, and PKCepsilon relative to controls. More...
cAMP-dependent protein kinase catalytic subunit a Ditzen C, 2012 patients and normal controls Regulated Protein in Cerebrospinal Fluid of Depressed Patien...... Regulated Protein in Cerebrospinal Fluid of Depressed Patients More...

Positive relationships between cAMP-dependent protein kinase catalytic subunit alpha and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment

Positive relationship network of cAMP-dependent protein kinase catalytic subunit alpha in MK4MDD
Network loading ...

network_footer.jsp Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between cAMP-dependent protein kinase catalytic subunit alpha and MDD (count: 0)
Negative relationships between cAMP-dependent protein kinase catalytic subunit alpha and other components at different levels (count: 0) Help
Related Gene Info
Gene Symbol Gene Name Type No. of Studies (Positive/Negative) Add to Relationship Set
PRKACA protein kinase, cAMP-dependent, catalytic, alpha Protein mapped 0 (0/0)