Gene Report

Basic Information

Approved Symbol	SYNPO2
Approved Name	synaptopodin 2
Symbol Alias	MYOPODIN
Location	4q26
Position	chr4:119809996-119982402 (+)
External Links	Entrez Gene: 171024 Ensembl: ENSG00000172403 UCSC: uc010inb.3 HGNC ID: 17732
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between SYNPO2 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
SYNPO2	Sequeira, 2007	patients and normal controls		Selected differentially expressed genes in hippocampus Selected differentially expressed genes in hippocampus

Positive relationships between SYNPO2 and other components at different levels (count: 1)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
Name in Literature	Related Components
SYNPO2		Hippocampus(hippocampus)	brain morphology and function	Sequeira, 2007	patients and normal controls		Selected differentially expressed genes in hippocampus Selected differentially expressed genes in hippocampus

Positive relationship network of SYNPO2 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between SYNPO2 and MDD (count: 0)

Negative relationships between SYNPO2 and other components at different levels (count: 0)

SYNPO2 related SNPs in MK4MDD (count: 0)

SYNPO2 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Synaptopodin-2	Q9UMS6	0(0/0)	Gene mapped

SYNPO2 related GO terms (count: 7)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0051371	muscle alpha-actinin binding	molecular function	ISS
GO:0030018	Z disc	cellular component	ISS
GO:0005515	protein binding	molecular function	IPI
GO:0005634	nucleus	cellular component	ISS
GO:0071889	14-3-3 protein binding	molecular function	ISS
GO:0003779	actin binding	molecular function	IEA
GO:0015629	actin cytoskeleton	cellular component	IDA

SYNPO2 related KEGG pathways (count: 0)

SYNPO2 related BioCarta pathways (count: 0)

SYNPO2 related Reactome pathways (count: 0)

SYNPO2 related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Gene mapped GO terms