Gene Report

Basic Information

Approved Symbol	PPTC7
Approved Name	PTC7 protein phosphatase homolog (S. cerevisiae)
Symbol Alias	TA-PP2C
Name Alias	T cell activation protein phosphatase 2C
Location	12q24.11
Position	chr12:110972237-111021064 (-)
External Links	Entrez Gene: 160760 Ensembl: ENSG00000196850 UCSC: uc001trh.1 HGNC ID: 30695
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between PPTC7 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
TA-PP2C	Sequeira, 2007	patients and normal controls		Selected differentially expressed genes in hippocampus Selected differentially expressed genes in hippocampus

Positive relationships between PPTC7 and other components at different levels (count: 1)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
Name in Literature	Related Components
TA-PP2C		Hippocampus(hippocampus)	brain morphology and function	Sequeira, 2007	patients and normal controls		Selected differentially expressed genes in hippocampus Selected differentially expressed genes in hippocampus

Positive relationship network of PPTC7 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between PPTC7 and MDD (count: 0)

Negative relationships between PPTC7 and other components at different levels (count: 0)

PPTC7 related SNPs in MK4MDD (count: 0)

PPTC7 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Protein phosphatase PTC7 homolog	Q8NI37	0(0/0)	Gene mapped

PPTC7 related GO terms (count: 3)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0046872	metal ion binding	molecular function	IEA
GO:0005739	mitochondrion	cellular component	IEA
GO:0004721	phosphoprotein phosphatase activity	molecular function	IEA

PPTC7 related KEGG pathways (count: 0)

PPTC7 related BioCarta pathways (count: 0)

PPTC7 related Reactome pathways (count: 0)

PPTC7 related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Gene mapped GO terms