MK4MDD

Gene Report

Basic Information
Approved Symbol PPM1K
Approved Name protein phosphatase, Mg2+/Mn2+ dependent, 1K
Previous Name "protein phosphatase 1K (PP2C domain containing)"
Symbol Alias DKFZp761G058, PP2Ckappa, hPTMP, PP2Cm, BDP
Name Alias "PP2C-type mitochondrial phosphoprotein phosphatase", "protein phosphatase 2C kappa", "branched-chain α-ketoacid dehydrogenase phosphatase"
Location 4q22.1
Position chr4:89205558-89205771 (-)
External Links Entrez Gene: 152926
Ensembl: ENSG00000163644
UCSC: uc003hrm.5
HGNC ID: 25415
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between PPM1K and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
PPM1K Sequeira, 2007 patients and normal controls Selected differentially expressed genes in hippocampus Selected differentially expressed genes in hippocampus

Positive relationships between PPM1K and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of PPM1K in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between PPM1K and MDD (count: 0)
Negative relationships between PPM1K and other components at different levels (count: 0) Help
PPM1K related SNPs in MK4MDD (count: 0)
PPM1K related proteins in MK4MDD (count: 0)
PPM1K related GO terms (count: 9)
PPM1K related KEGG pathways (count: 0)
PPM1K related BioCarta pathways (count: 0)
PPM1K related Reactome pathways (count: 0)
PPM1K related interactors from protein-protein interaction data in HPRD (count: 0)