MK4MDD

Gene Report

Basic Information
Approved Symbol PCSK2
Approved Name proprotein convertase subtilisin/kexin type 2
Previous Symbol NEC2
Symbol Alias PC2, SPC2
Name Alias "neuroendocrine convertase 2", "KEX2-like endoprotease 2"
Location 20p11.2
Position chr20:17462716-17465223 (+)
External Links Entrez Gene: 5126
Ensembl: ENSG00000125851
UCSC: uc002wpm.3
HGNC ID: 8744
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between PCSK2 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
PCSK2 Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder

Positive relationships between PCSK2 and other components at different levels (count: 0) Help
Positive relationship network of PCSK2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between PCSK2 and MDD (count: 0)
Negative relationships between PCSK2 and other components at different levels (count: 0) Help
PCSK2 related SNPs in MK4MDD (count: 0)
PCSK2 related proteins in MK4MDD (count: 0)
PCSK2 related GO terms (count: 16)
PCSK2 related KEGG pathways (count: 0)
PCSK2 related BioCarta pathways (count: 0)
PCSK2 related Reactome pathways (count: 2)
PCSK2 related interactors from protein-protein interaction data in HPRD (count: 3)