Protein Report

Basic Information

Protein Name	Oxytocin-neurophysin 1
UniPortKB	P01178
No. of Studies (Positive/Negative)	2 (2/0)
Type	Literature-origin

Positive relationship between Oxytocin-neurophysin 1 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
oxytocin	Parker, 2010	patients and normal controls		Results indicated that depressed subjects exhibit increased ...... Results indicated that depressed subjects exhibit increased OT (oxytocin) levels compared to healthy control subjects, and this difference is most apparent during the nocturnal peak. More...

Positive relationships between Oxytocin-neurophysin 1 and other components at different levels (count: 2)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description
Name in Literature	Related Components
oxytocin		Increased agitation(anxiety)	symptoms	Scantamburlo, 2007	patients only	r=-0.61, P-value=0.005	Results showed a significant negative correlation between ox...... Results showed a significant negative correlation between oxytocin and the scored symptoms depression (r=-0.58, p=0.003) and anxiety (r=-0.61, p=0.005). More...
oxytocin		Depressed mood(depression)	symptoms	Scantamburlo, 2007	patients only	r=-0.58, P-value=0.003	Results showed a significant negative correlation between ox...... Results showed a significant negative correlation between oxytocin and the scored symptoms depression (r=-0.58, p=0.003) and anxiety (r=-0.61, p=0.005). More...

Positive relationship network of Oxytocin-neurophysin 1 in MK4MDD

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network_footer.jsp Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between Oxytocin-neurophysin 1 and MDD (count: 0)

Negative relationships between Oxytocin-neurophysin 1 and other components at different levels (count: 0)

Related Gene Info

Gene Symbol	Gene Name	Type	No. of Studies (Positive/Negative)	Add to Relationship Set
OXT	oxytocin/neurophysin I prepropeptide	Protein mapped	0 (0/0)