Neurobiological Component Report

Name	Non rapid-eye movement (REM) sleep
Description	Non-rapid eye movement, or NREM is, collectively, sleep stages 1 - 3, previously known as stages 1 - 4. Rapid eye movement sleep (REM) is not included. There are distinct electroencephalographic and other characteristics seen in each stage. Unlike REM sleep, there is usually little or no eye movement during this stage. Dreaming is rare during NREM sleep, and muscles are not paralyzed as in REM sleep. In addition, there is a parasympathetic dominance during NREM.
No. of Studies (Positive/Negative)	2 (2/0)

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
non rapid-eye movement (REM) sleep		Hydrocortisone(cortisol)	molecule	Schmid, 2008	patients only		Cortisol increased duration and intensity of non-REM sleep i...... Cortisol increased duration and intensity of non-REM sleep in particular in male patients and stimulated GH release. More...
higher NonREM sigma power		Hydrocortisone(cortisol)	molecule	Friess, 2008	patients and normal controls		Dexamethasone suppressed cortisol levels were positively ass...... Dexamethasone suppressed cortisol levels were positively associated with higher NonREM sigma power after merging the three groups. More...
non rapid-eye movement (REM) sleep		Hypothalamic-pituitary-adrenal axis(HPA axis)	neurobiological system	Schmid, 2008	patients only		The activity of the HPA axis appeared to influence the corti...... The activity of the HPA axis appeared to influence the cortisol-induced effects on non-REM sleep and GH levels. More...

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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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