Brain Morphology and Function Report

Name	Middle frontal gyrus
Brain Morphology	The middle frontal gyrus makes up about one-third of the frontal lobe of the human brain. (A gyrus is one of the prominent "bumps" or "ridges" on the surface of the human brain.) The middle frontal gyrus, like the inferior frontal gyrus and the superior frontal gyrus, is more of a region than a true gyrus. The borders of the middle frontal gyrus are the inferior frontal sulcus below; the superior frontal sulcus above; and the precentral sulcus behind.
Picture	From Wiki.
No. of Studies (Positive/Negative)	8(8/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
midfrontal gyrus	Smoski, 2009	patients and normal controls		MDD participants showed decreased activation of the middle f...... MDD participants showed decreased activation of the middle frontal gyrus during reward selection and anticipation. More...
middle frontal gyrus	Wang, 2008	patients and normal controls		Patients also revealed a reversed activation pattern from co...... Patients also revealed a reversed activation pattern from controls in response to this contrast in the bilateral middle frontal gyrus. More...
middle frontal gyrus	Wagner, 2008	patients and normal controls		Voxel-based morphometry (VBM) revealed grey matter decreases...... Voxel-based morphometry (VBM) revealed grey matter decreases in the middle frontal gyrus. More...
midfrontal gyrus	Dichter, 2009	patients and normal controls		During neutral blocks, the control group demonstrated greate...... During neutral blocks, the control group demonstrated greater activation to targets in the midfrontal gyrus and anterior cingulate relative to the MDD group, replicating previous findings of prefrontal hypo-activation in MDD samples to cognitive control stimuli. More...
middle frontal gyrus	Rasgon, 2008	patients and normal controls		Findings include hypermetabolism in the middle frontal gyrus...... Findings include hypermetabolism in the middle frontal gyrus among depressed compared with non-depressed women. More...
middle frontal gyri	Abe, 2010	patients and normal controls		Local areas showing significant gray matter volume reduction...... Local areas showing significant gray matter volume reduction in depressive patients compared with controls were observed in the bilateral middle frontal gyri. More...
middle frontal gyrus	Liu, 2010	patients and normal controls	P-value < 0.01	ReHo(regional homogeneity) in the MD group decreased in the ...... ReHo(regional homogeneity) in the MD group decreased in the left middle frontal gyrus, right middle frontal gyrus(P<0.01). More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
middle frontal gyrus		Orbitofrontal cortex(orbitofrontal volumes)	brain morphology and function	Scheuerecker, 2010	patients and normal controls		Within this cerebral network, the orbitofrontal volumes were...... Within this cerebral network, the orbitofrontal volumes were negatively correlated in depressed patients but not in healthy controls with changes in blood oxygen level-dependent signal in the middle frontal gyrus, caudate nucleus, precuneus and supplementary motor area. More...
midfrontal gyrus		Depressed mood(depressed mood)	symptoms	Smoski, 2009	patients and normal controls		Depression severity was predicted by activation in bilateral...... Depression severity was predicted by activation in bilateral midfrontal gyrus during reward selection. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web