MK4MDD

Protein Report

Basic Information
Protein Name Leptin
UniPortKB P41159
No. of Studies (Positive/Negative) 3 (3/0) Help
Type Literature-origin
Positive relationship between Leptin and MDD (count: 3)
Name in Literature Reference Research Type Statistical Result Relation Description Help
leptin Westling, 2004 patients only P-value<0.01 women in the MDD group had lower CSF(cerebrospinal fluid) le...... women in the MDD group had lower CSF(cerebrospinal fluid) leptin than those in the non-MDD group (P < 0.01). More...
leptin Jow, 2006 patients and normal controls leptin and cholesterol levels were low in patients with majo...... leptin and cholesterol levels were low in patients with major depressive disorder More...
leptin Cizza, 2010 patients and normal controls mean nocturnal leptin concentration was higher in the MDD ve...... mean nocturnal leptin concentration was higher in the MDD versus control groups More...

Positive relationships between Leptin and other components at different levels (count: 2) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment

Positive relationship network of Leptin in MK4MDD
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network_footer.jsp Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Leptin and MDD (count: 0)
Negative relationships between Leptin and other components at different levels (count: 0) Help
Related Gene Info
Gene Symbol Gene Name Type No. of Studies (Positive/Negative) Add to Relationship Set
LEP leptin Protein mapped 0 (0/0)