Brain Morphology and Function Report

Name	Internal capsule
Brain Morphology	The internal capsule is an area of white matter in the brain that separates the caudate nucleus and the thalamus from the lenticular nucleus. The internal capsule contains both ascending and descending axons. It consists of axonal fibres that run between the cerebral cortex and the pyramids of the medulla.
No. of Studies (Positive/Negative)	3(3/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
internal capsule	Zou, 2008	patients and normal controls		We found a significant decrease in fractional anisotropy (FA...... We found a significant decrease in fractional anisotropy (FA) in the left hemisphere, including the anterior limb of the internal capsule and the inferior parietal portion of the superior longitudinal fasciculus, in patients with MDD compared with healthy controls. Diffusion tensor imaging measures in the left anterior limb of the internal capsule were negatively related to the severity of depressive symptoms. More...
internal capsule	Zhu, 2011	patients and normal controls		Compared with healthy controls, patients with MDD showed dec...... Compared with healthy controls, patients with MDD showed decreased fractional anisotropy (FA) values in three WM tracts: the left anterior limb of the internal capsule, the right parahippocampal gyrus, and the left posterior cingulate cortex. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
internal capsule		Suicide(suicide attempters)	symptoms	Jia, 2010	patients and normal controls		Fractional anisotropy was decreased in the left anterior lim...... Fractional anisotropy was decreased in the left anterior limb of the internal capsule in suicide attempters relative to both nonattempters and healthy comparison subjects More...
internal capsule		Depressed mood(depressive symptoms)	symptoms	Zhu, 2011	patients and normal controls		Further analysis revealed that FA (fractional anisotropy) va...... Further analysis revealed that FA (fractional anisotropy) values in the left anterior limb of the internal capsule were negatively correlated with the severity of depressive symptoms. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web