Brain Morphology and Function Report

Name	Grey matter
Brain Morphology	Grey matter (or gray matter) is a major component of the central nervous system, consisting of neuronal cell bodies, neuropil (dendrites and both unmyelinated axons and myelinated axons), glial cells (astroglia and oligodendrocytes) and capillaries. Grey matter contains neural cell bodies, in contrast to white matter, which does not and mostly contains myelinated axon tracts. The color difference arises mainly from the whiteness of myelin. In living tissue, grey matter actually has a grey-brown color, which comes from capillary blood vessels and neuronal cell bodies.
Brain Function	Grey matter is made up of neuronal cell bodies. The grey matter includes regions of the brain involved in muscle control, sensory perception such as seeing and hearing, memory, emotions, and speech.
No. of Studies (Positive/Negative)	3(2/1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
gray matter	Hwang, 2010	patients and normal controls		Late-onset depression was associated with smaller volumes in...... Late-onset depression was associated with smaller volumes in several regions of gray matter (insula and the posterior cingulate region) More...
gray matter volume	Inkster, 2011	patients and normal controls		The MDD patients together showed lower GM volume than health...... The MDD patients together showed lower GM volume than healthy controls in the superior parietal lobe. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
gray matter volume		Increased agitation(anxiety)	symptoms	Inkster, 2011	patients and normal controls	P(FWE) = .002	MDD+A patients had greater gray matter (GM) volume (P(FWE) =...... MDD+A patients had greater gray matter (GM) volume (P(FWE) = .002) than MDD-A patients in the right temporal cortex extending from the mid-posterior superior temporal gyrus into the posterior middle and inferior temporal gyrus. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
gray matter	Kumar, 2002	patients and normal controls		The groups had no significant differences in the metabolite ...... The groups had no significant differences in the metabolite ratios in the gray matter. More...