Brain Morphology and Function Report

Name	Default mode network
Brain Function	Regions in a separate system, the default mode network (DMN), are defined functionally by their coordinated behavior and commonly have the greatest activity at rest and decreased activity during the performance of goal-directed tasks. The DMN is important in self-referential activities, including evaluating salience of internal and external cues, remembering the past, and planning the future (PMID: 20534464).
No. of Studies (Positive/Negative)	2(2/0)

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
default mode network		dorsal medial prefrontal cortex region(dorsal medial prefrontal cortex region)	brain morphology and function	Sheline, 2010	patients and normal controls		Three different brain networks--the cognitive control networ...... Three different brain networks--the cognitive control network, default mode network, and affective network--were investigated. Compared with controls, in depressed subjects each of these three networks had increased connectivity to the same bilateral dorsal medial prefrontal cortex region More...
default-mode network (DMN)		Rumination(rumination)	symptoms	Hamilton, 2011	patients and normal controls		In the MDD participants, increasing levels of DMN dominance ...... In the MDD participants, increasing levels of DMN dominance were associated with higher levels of maladaptive, depressive rumination and lower levels of adaptive, reflective rumination. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web