Symptoms Report

Name	Decreased appetite
Description	A depressed person may report multiple physical symptoms. Appetite often decreases, with resulting weight loss, although increased appetite and weight gain occasionally occur.
No. of Studies (Positive/Negative)	6 (6/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
loss of appetite	Taylor, 2010	patients only	P-value < .05	Decreased agitation, increased psychological anxiety, increa...... Decreased agitation, increased psychological anxiety, increased loss of appetite, increased loss of libido, and increased hypochondriasis were all risk factors for relapse and recurrence over a 2-year follow-up (all p<.05), after stratifying on number of previous episodes and controlling for age at onset and whether A-CT responders received continuation phase CT instead of assessment only control. More...
weight loss	Ludman, 2010	patients and normal controls	At 6 months, women with MDD lost a mean of 3.8 kg vs 4.3 kg for women without MDD (t = 0.54, p = .59). At 12 months, women with MDD lost 3.0 kg and women without MDD lost 3.6 kg (t = 0.44, p =.66).	At 6 months, women with MDD lost a mean of 3.8 kg vs 4.3 kg ...... At 6 months, women with MDD lost a mean of 3.8 kg vs 4.3 kg for women without MDD (t = 0.54, p = .59). At 12 months, women with MDD lost 3.0 kg and women without MDD lost 3.6 kg (t = 0.44, p =.66). Results suggest that depression should not be an exclusion criterion for weight loss intervention programs. More...
reduced appetite	Roca, 2011	patients only	adjusted odds ratio, 1.2	First-episode patients (those diagnosed of their first major...... First-episode patients (those diagnosed of their first major depressive disorder) were more likely to experience reduced appetite (adjusted odds ratio, 1.2) and suicidal thoughts (adjusted odds ratio, 1.2). More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
loss of appetite		N100(N1)	neurobiological system	Linka, 2009	patients only		Our data revealed a positive correlation of the intensity de...... Our data revealed a positive correlation of the intensity dependent N1 amplitude slope with the degree of certain somatic symptoms of depression: loss of appetite and weight, insomnia, and sexual dysfunction. More...
loss of weight		N100(N1)	neurobiological system	Linka, 2009	patients only		Our data revealed a positive correlation of the intensity de...... Our data revealed a positive correlation of the intensity dependent N1 amplitude slope with the degree of certain somatic symptoms of depression: loss of appetite and weight, insomnia, and sexual dysfunction. More...
weight loss		Sleep disturbances(sleep disturbance)	symptoms	Liu, 2007	patients only		Across sleep-disturbed children, those with both insomnia an...... Across sleep-disturbed children, those with both insomnia and hypersomnia had a longer history of illness, were more severely depressed, and were more likely to have anhedonia, weight loss, psychomotor retardation, and fatigue than were those with either insomnia or hypersomnia. More...
weight loss		Psychotic symptoms(psychotic features)	symptoms	Gaudiano, 2008	patients only		Patients with PMD(patients with psychotic major depression) ...... Patients with PMD(patients with psychotic major depression) were more likely to endorse the presence of weight loss compared with NMD(nonpsychotic major depression) patients. More...

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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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