Neurobiological Component Report

Name	N100
Description	In neuroscience, the N100 or N1 is a large, negative-going evoked potential measured by electroencephalography; it peaks in adults between 80 and 120 milliseconds after the onset of a stimulus, and distributed mostly over the fronto-central region of the scalp. It is elicited by any unpredictable stimulus in the absence of task demands.
Picture	From Wiki.
No. of Studies (Positive/Negative)	3 (3/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
N1	Poulsen, 2009	patients and normal controls		For controls, the event-related potential (ERP) showed an en...... For controls, the event-related potential (ERP) showed an enhanced visual N1 for trials in which Bad traits were endorsed. For depressed participants, this N1 was attenuated, specifically for these endorsed Bad trials. More...
N1	Dai, 2011	patients and normal controls		The MDD participants showed a smaller N1 amplitude for negat...... The MDD participants showed a smaller N1 amplitude for negative words in bilateral hemispheres compared with the other groups. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
N1		Inferotemporal-occipital cortex(inferotemporal-occipital cortex)	brain morphology and function	Poulsen, 2009	patients and normal controls		Distributed linear-inverse source analysis of the ERP locali...... Distributed linear-inverse source analysis of the ERP localized the N1 effect to the inferotemporal-occipital cortex. More...
N1		Sleep disturbances(insomnia)	symptoms	Linka, 2009	patients only		Our data revealed a positive correlation of the intensity de...... Our data revealed a positive correlation of the intensity dependent N1 amplitude slope with the degree of certain somatic symptoms of depression: loss of appetite and weight, insomnia, and sexual dysfunction. More...
N1		Decreased appetite(loss of appetite)	symptoms	Linka, 2009	patients only		Our data revealed a positive correlation of the intensity de...... Our data revealed a positive correlation of the intensity dependent N1 amplitude slope with the degree of certain somatic symptoms of depression: loss of appetite and weight, insomnia, and sexual dysfunction. More...
N1		Decreased appetite(loss of weight)	symptoms	Linka, 2009	patients only		Our data revealed a positive correlation of the intensity de...... Our data revealed a positive correlation of the intensity dependent N1 amplitude slope with the degree of certain somatic symptoms of depression: loss of appetite and weight, insomnia, and sexual dysfunction. More...
N1		Sexual dysfunction(sexual dysfunction)	symptoms	Linka, 2009	patients only		Our data revealed a positive correlation of the intensity de...... Our data revealed a positive correlation of the intensity dependent N1 amplitude slope with the degree of certain somatic symptoms of depression: loss of appetite and weight, insomnia, and sexual dysfunction. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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3. The network is generated using Cytoscape Web