Gene Report

Basic Information

Approved Symbol	CAPRIN1
Approved Name	cell cycle associated protein 1
Previous Symbol	M11S1, GPIAP1
Previous Name	membrane component, chromosome 11, surface marker 1, "GPI-anchored membrane protein 1"
Symbol Alias	caprin-1, RNG105
Name Alias	cytoplasmic activation/proliferation-associated protein-1
Location	11p13
Position	chr11:34073230-34124157 (+)
External Links	Entrez Gene: 4076 Ensembl: ENSG00000135387 UCSC: uc001mvh.1 HGNC ID: 6743
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between CAPRIN1 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
CAPRIN1	Spijker, 2010	patients and normal controls		Based on LPS-stimulated blood gene expression using whole-ge...... Based on LPS-stimulated blood gene expression using whole-genome microarrays, this gene serves as a molecular signature of MDD More...

Positive relationships between CAPRIN1 and other components at different levels (count: 0)

Positive relationship network of CAPRIN1 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between CAPRIN1 and MDD (count: 0)

Negative relationships between CAPRIN1 and other components at different levels (count: 0)

CAPRIN1 related SNPs in MK4MDD (count: 0)

CAPRIN1 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Caprin-1	Q14444	0(0/0)	Gene mapped

CAPRIN1 related GO terms (count: 10)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0017148	negative regulation of translation	biological process	ISS
GO:0003723	RNA binding	molecular function	ISS
GO:0005887	integral to plasma membrane	cellular component	TAS[7657653]
GO:0061003	positive regulation of dendritic spine morphogenesis	biological process	ISS
GO:0010494	cytoplasmic stress granule	cellular component	ISS
GO:0005829	cytosol	cellular component	IEA
GO:0050775	positive regulation of dendrite morphogenesis	biological process	ISS
GO:0005737	cytoplasm	cellular component	IDA
GO:0030425	dendrite	cellular component	IEA
GO:0000932	cytoplasmic mRNA processing body	cellular component	ISS

CAPRIN1 related KEGG pathways (count: 0)

CAPRIN1 related BioCarta pathways (count: 0)

CAPRIN1 related Reactome pathways (count: 0)

CAPRIN1 related interactors from protein-protein interaction data in HPRD (count: 1)

Gene Report

Gene mapped GO terms