MK4MDD

Brain Morphology and Function Report

Basic Information
Name Brainstem
Brain Morphology "The brainstem is the posterior part of the brain, adjoining and structurally continuous with the spinal cord. The brain stem is made of the midbrain, pons, and medulla."
Brain Function "Brain stem is responsible for basic vital life functions such as breathing, heartbeat, and blood pressure. "
Picture Brainstem Source Magnify
No. of Studies (Positive/Negative) 6(6/0) Help

Positive relationships between Brainstem and MDD (count: 5)
Name in Literature Reference Research Type Statistical Result Relation Description Help
brainstem Kumar, 2008 patients and normal controls The TD (temporal difference) signal was increased in the bra...... The TD (temporal difference) signal was increased in the brainstem of depressed patients. More...
brain stem Kimbrell, 2002 patients and normal controls Compared with control subjects, the subgroup of patients wit...... Compared with control subjects, the subgroup of patients with Hamilton depression scores of 22 or greater exhibited increased normalized metabolic activity bilaterally in the brain stem. More...
brainstem Agid, 2003 patients and normal controls P-value = 0.004 Mean volume of T2-WIH was significantly greater (p=0.004) in...... Mean volume of T2-WIH was significantly greater (p=0.004) in depressed subjects. In the control group T2-WIH(T2-weighted image 'hyperintensities') were exclusively located in the supratentorial hemispheral white matter while in the depressed group T2-WIH were also found in basal ganglia, temporal lobe, cerebellum and brainstem. More...
brainstem Walter, 2007 patients and normal controls Transcranial sonography (TCS) revealed reduced brainstem rap...... Transcranial sonography (TCS) revealed reduced brainstem raphe (BR) echogenicity in major depressive disorder (MDD). More...
brain stem Selvaraj, 2011 patients and normal controls The depressed patients had lowered 5-HTT binding in several ...... The depressed patients had lowered 5-HTT binding in several brain regions including brain stem More...

Positive relationships between Brainstem and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Brainstem in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Brainstem and MDD (count: 0)
Negative relationships between Brainstem and other components at different levels (count: 0) Help