MK4MDD

Brain Morphology and Function Report

Basic Information
Name Attention network
Brain Morphology "The ventral attention network (VAN) is one of two sensory orienting systems in the human brain, the other being the dorsal attention network. Its main function is to reorient attention towards salient stimuli. The VAN is considered to be involved mostly, if not entirely, in involuntary actions. The neural network is right hemisphere lateralized and includes the right temporal-parietal junction and the right ventral frontal cortex. This system shows activity increases upon detection of salient targets, especially when they appear in unexpected locations. Activity increases also are observed in the ventral system after abrupt changes in sensory stimuli, at the onset and offset of task blocks, and at the end of a completed trial. The ventral attention network is one of several low frequency resting state networks in the brain. The others include the dorsal attention network and the default network. The dorsal attention network (DAN) is involved in voluntary (top-down) orienting and shows activity increases after presentation of cues indicating where, when, or to what subjects should direct their attention. The dorsal attention network is bilateral and includes the intraparietal sulcus and the junction of the precentral and superior frontal sulcus (frontal eye fields) in each hemisphere."
No. of Studies (Positive/Negative) 19(19/0) Help

Positive relationships between Attention network and MDD (count: 8)
Name in Literature Reference Research Type Statistical Result Relation Description Help
frontal cortex Grimm, 2008 patients and normal controls The MDD patients showed hypoactivity in the left DLPFC durin...... The MDD patients showed hypoactivity in the left DLPFC during both unattended and attended emotional judgment. More...
frontal cortex Pagani, 2004 patients and normal controls P<0.025 As compared to normal controls, MDD rCBF (regional cerebral ...... As compared to normal controls, MDD rCBF (regional cerebral blood flow) was relatively higher in frontal cortex ( P<0.025), More...
frontal cortex Graff-Guerrero, 2004 patients only The frontal cortex plays an important role in the expression...... The frontal cortex plays an important role in the expression of MDD symptoms. More...
frontal cortex Nofzinger, 2005 patients and normal controls Depressed patients showed smaller decreases than healthy sub...... Depressed patients showed smaller decreases than healthy subjects in relative metabolism in broad regions of the frontal cortex from waking to NREM sleep. More...
frontal cortex Kohn, 2007 patients and normal controls Baseline rCBF (regional cerebral blood flow) was lower in de...... Baseline rCBF (regional cerebral blood flow) was lower in depressed patients than in controls in the frontal cortex and subcortical nuclei bilaterally. More...
frontal cortex Michopoulos, 2008 patients and normal controls MDD patients showed neuropsychological deficits on tasks of ...... MDD patients showed neuropsychological deficits on tasks of executive function and memory, supporting the model of frontal-temporal dysfunction More...
frontal cortex Selvaraj, 2011 patients and normal controls The depressed patients had lowered 5-HTT binding in several ...... The depressed patients had lowered 5-HTT binding in several brain regions including frontal cortex. More...
frontal cortex Jiao, 2011 patients and normal controls Resting brain activity levels measured by ALFF was higher in...... Resting brain activity levels measured by ALFF was higher in the frontal cortex than that in the subcortical system involving mainly (para) limbic-striatal regions in both HC and MDD adolescents. More...

Positive relationships between Attention network and other components at different levels (count: 12) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Attention network in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Attention network and MDD (count: 0)
Negative relationships between Attention network and other components at different levels (count: 0) Help
Attention network involved components (count: 2)
Name Type  
Temporo-parietal connection brain morphology and function
Frontal Lobe brain morphology and function