Brain Morphology and Function Report

Basic Information

Name	Affective network
Brain Morphology	The affective network (AN), comprises the connections of the affective division of the anterior cingulate cortex (ACC: subgenual and pregenual cingulate).
Brain Function	The affective network is involved in emotional processing and, through its connections with other regions, is important in fear, vigilance, and autonomic and visceral regulation (PMID: 20534464).
Picture	From Wiki.
No. of Studies (Positive/Negative)	3(3/0)

Positive relationships between Affective network and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
emotional circuitry	Fales, 2008	patients and normal controls		These results suggest multiple sources of dysregulation in e...... These results suggest multiple sources of dysregulation in emotional circuitry in depression, implicating both top-down and bottom-up dysfunction. More...

Positive relationships between Affective network and other components at different levels (count: 5)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Relation Description
Name in Literature	Related Components
affective network		dorsal medial prefrontal cortex region(dorsal medial prefrontal cortex region)	brain morphology and function	Sheline, 2010	patients and normal controls	Three different brain networks--the cognitive control networ...... Three different brain networks--the cognitive control network, default mode network, and affective network--were investigated. Compared with controls, in depressed subjects each of these three networks had increased connectivity to the same bilateral dorsal medial prefrontal cortex region More...
emotional circuit		Amygdala(amygdala (AMY))	brain morphology and function	Carballedo, 2011	patients and normal controls	The aim of the study is to map a neural network of emotion p...... The aim of the study is to map a neural network of emotion processing. A valid model was established for the left and the right hemispheres showing a circuit involving ACC, OFC, PFC and AMY(amygdala). More...
emotional circuit		Anterior cingulate cortex(anterior cingulate cortex (ACC))	brain morphology and function	Carballedo, 2011	patients and normal controls	The aim of the study is to map a neural network of emotion p...... The aim of the study is to map a neural network of emotion processing. A valid model was established for the left and the right hemispheres showing a circuit involving ACC, OFC, PFC and AMY. More...
emotional circuit		Orbitofrontal cortex(orbitofrontal cortex (OFC))	brain morphology and function	Carballedo, 2011	patients and normal controls	The aim of the study is to map a neural network of emotion p...... The aim of the study is to map a neural network of emotion processing. A valid model was established for the left and the right hemispheres showing a circuit involving ACC, OFC, PFC and AMY. More...
emotional circuit		Prefrontal cortex(prefrontal cortex (PFC))	brain morphology and function	Carballedo, 2011	patients and normal controls	The aim of the study is to map a neural network of emotion p...... The aim of the study is to map a neural network of emotion processing. A valid model was established for the left and the right hemispheres showing a circuit involving ACC, OFC, PFC and AMY. More...

Positive relationship network of Affective network in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between Affective network and MDD (count: 0)

Negative relationships between Affective network and other components at different levels (count: 0)

Affective network involved components (count: 6)

Name	Type
Cingulate gyrus	brain morphology and function
Hypothalamus	brain morphology and function
Amygdala	brain morphology and function
Entorhinal cortex	brain morphology and function
Nucleus accumbens	brain morphology and function
Limbic lobe	brain morphology and function