MK4MDD

Protein Report

Basic Information
Protein Name 5-hydroxytryptamine receptor 1B
UniPortKB P28222
No. of Studies (Positive/Negative) 2 (2/0) Help
Type Literature-origin
Positive relationship between 5-hydroxytryptamine receptor 1B and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
5-HT(1B) receptor Murrough, 2011 patients and normal controls P-value < 0.001 Within the ventral striatum/ventral pallidum region of inter...... Within the ventral striatum/ventral pallidum region of interest, 5-HT(1B) receptor radioligand [(11)C]P943 BP (ND) was significantly reduced in the MDD group compared with the healthy control group (1.37 +/- 0.13 and 1.68 +/- 0.16, respectively; 18.7% between-group difference; p < 0.001). More...

Positive relationships between 5-hydroxytryptamine receptor 1B and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment

Positive relationship network of 5-hydroxytryptamine receptor 1B in MK4MDD
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network_footer.jsp Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between 5-hydroxytryptamine receptor 1B and MDD (count: 0)
Negative relationships between 5-hydroxytryptamine receptor 1B and other components at different levels (count: 0) Help
Related Gene Info
Gene Symbol Gene Name Type No. of Studies (Positive/Negative) Add to Relationship Set
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled Literature-origin; Protein mapped 5 (4/1)