MK4MDD

Molecule Report

Basic Information
Name 3-Hydroxyanthranilic Acid
Description An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
MeSH ID D015095
No. of Studies (Positive/Negative) 2(1/1) Help

Positive relationship between 3-Hydroxyanthranilic Acid and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
3-hydroxyanthranilic acid (3-HAA, neurotoxic metabolite) Gabbay, 2010 patients and normal controls P-value<0.05 Positive correlations were found only in the melancholic gro...... Positive correlations were found only in the melancholic group, between KYN and 3-HAA and tCho in the right caudate (r=0.93, p=0.03) and the left putamen (r=0.96, p=.006), respectively. More...

Positive relationships between 3-Hydroxyanthranilic Acid and other components at different levels (count: 0) Help
Positive relationship network of 3-Hydroxyanthranilic Acid in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationship between 3-Hydroxyanthranilic Acid and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
3-HAA Hughes MM, 2012 patients and normal controls There was no difference between controls and depressives in ...... There was no difference between controls and depressives in concentrations of KYNA and 3-HAA, or in expression of enzymes KAT, KMO or kynureninase that drive their production. More...

Negative relationships between 3-Hydroxyanthranilic Acid and other components at different levels (count: 0) Help