Study Report
Reference
| Citation | Pasquini, 2008 PubMed |
| Full Info | Pasquini, M., Speca, A., Mastroeni, S., Delle Chiaie, R., Sternberg, C.N. and Biondi, M. (2008) Differences in depressive thoughts between major depressive disorder, IFN-alpha-induced depression, and depressive disorders among cancer patients. J Psychosom Res, 65, 153-156.
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Study
| Hypothesis or Background |
The objective of this study is to test the hypothesis that there are differences in the distribution of negative thoughts among major depressive disorders (MDD), depressive disorders among cancer patients, and IFN-alpha-induced depression.
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| Sample Information | Twenty-three patients affected by MDD, 25 cancer patients affected by depressive disorders (20 MDD), and 19 patients affected by IFN-alpha-induced depression satisfying MDD criteria |
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| Method Detail | Subjects were evaluated using the 17-item Hamilton Depression Rating Scale and the 13-item Beck Depression Inventory. |
| Method Keywords | clinical test |
| Result | Sense of guilt was higher among MDD patients (56.5%) and was lower among cancer patients (4%) (P<.0001). Sense of failure, dissatisfaction, and self-dislike were higher among MDD patients than among IFN-alpha patients (P<.0001). |
| Conclusions | In our study, patients affected by MDD present a different pattern of symptoms in comparison with patients affected by IFN-alpha-induced depression and depressive disorders. In particular, core depressive thoughts were less frequent in the last two conditions. |
Relationships reported by
Pasquini, 2008
| Component A Approved Name (Name in Paper) |
Component A Type |
Component B Approved Name (Name in Paper) |
Component B Type |
Statistical Result |
Relationship Description |
Result Category (Positive/Negative)) |
|
MDD
|
syndrome |
Feelings of hopelessness, worthlessness, and guilt (sense of guilt) |
symptoms |
P-value <.0001 |
Sense of guilt was higher among MDD patients (56.5%) and was lower among cancer patients (4%) (P<.0001). |
Positive
|
|
MDD
|
syndrome |
Feelings of hopelessness, worthlessness, and guilt (sense of failure, dissatisfaction, and self-dislike) |
symptoms |
P-value <.0001 |
Sense of failure, dissatisfaction, and self-dislike were higher among MDD patients than among IFN-alpha patients (P<.0001). |
Positive
|
