Study Report
Reference
| Citation | Abou-Saleh, 1989 PubMed |
| Full Info | Abou-Saleh, M.T. and Coppen, A. (1989) Serum and red blood cell folate in depression. Acta Psychiatr Scand, 80, 78-82
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Study
| Hypothesis or Background |
|
| Sample Information | patients with major depressive disorders, lithium-treated patients, detoxified alcoholic patients and normal controls |
|---|
| Method Detail | Serum folate concentrations were estimated in patients with major depressive disorders, lithium-treated patients, detoxified alcoholic patients and normal controls. Red blood cell (RBC) folate concentrations were also estimated in subgroups of patients with major depressive disorder and normal controls. |
| Method Keywords | blood analysis |
| Result | Results showed significantly lower serum and RBC folate concentrations in patients with major depressive disorder than in normal controls. Lower serum folate concentrations were associated with greater severity of depression. There was no association between serum and RBC folate concentrations and endogenicity of depression or the presence of weight loss. |
Relationships reported by
Abou-Saleh, 1989
| Component A Approved Name (Name in Paper) |
Component A Type |
Component B Approved Name (Name in Paper) |
Component B Type |
Statistical Result |
Relationship Description |
Result Category (Positive/Negative)) |
|
MDD
|
syndrome |
Folic Acid (folate) |
molecule |
|
Results showed significantly lower serum and RBC folate concentrations in patients with major depressive disorder than in normal controls. |
Positive
|
|
MDD
|
syndrome |
Erythrocyte (Red blood cell) |
cell |
|
Results showed significantly lower serum and RBC folate concentrations in patients with major depressive disorder than in normal controls. |
Positive
|
