Study Report
Reference
| Citation | Levitt, 1989 PubMed |
| Full Info | Levitt, A.J. and Joffe, R.T. (1989) Folate, B12, and life course of depressive illness. Biol Psychiatry, 25, 867-872.
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Study
| Hypothesis or Background |
|
| Sample Information | Forty-four consecutive, unmedicated outpatients with a major depressive |
|---|
| Method Detail | Forty-four consecutive, unmedicated outpatients with a major depressive disorder were evaluated to determine the relationships in life course, severity of depressive illness, and serum folate and B12 levels. |
| Method Keywords | |
| Result | Duration of current episode was significantly inversely correlated with folate levels. Age at onset of illness was significantly correlated with B12. In a subgroup of recurrent depressives, current age and age at onset of depressive illness were positively correlated with folate. |
| Conclusions | The findings are discussed in light of the current hypotheses regarding the association of folate and mood. |
Relationships reported by
Levitt, 1989
| Component A Approved Name (Name in Paper) |
Component A Type |
Component B Approved Name (Name in Paper) |
Component B Type |
Statistical Result |
Relationship Description |
Result Category (Positive/Negative)) |
|
MDD
|
syndrome |
Folic Acid (folate) |
molecule |
|
Duration of current episode was significantly inversely correlated with folate levels. |
Positive
|
