MK4MDD

SNP Report

Basic Information
Name rs9939609 dbSNP Ensembl
Location Chrchr16:53786615(Forward)
Variant Alleles T/A
Ancestral Allele A
No. of Studies (Positive/Negative) 2 (1/1) Help

Positive relationship between rs9939609 and MDD (count: 1)
Reference Research Type Statistical Result Relation Description Help
Samaan Z, 2012 patients and normal controls odds ratio=0.92 (0.89, 0.97), P-value =3 x 10(-4) A meta-analysis of the four studies showed a significant inv...... A meta-analysis of the four studies showed a significant inverse association between the obesity risk FTO rs9939609 A variant and depression (odds ratio=0.92 (0.89, 0.97), P=3 x 10(-4)) adjusted for age, sex, ethnicity/population structure and body-mass index (BMI) with no significant between-study heterogeneity (I(2)=0%, P=0.63). More...

Relationships between rs9939609 and other components at different levels (count: 0) Help
Positive relationship network of rs9939609 in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between rs9939609 and MDD (count: 1)
Reference Research Type Statistical Result Relation Description
Du, 2015 Patients and nomal controls P(allele)=0.5586£»P(genotype)=0.6641 SNP rs12936694 in the ALKBH5 locus was strongly associated w...... SNP rs12936694 in the ALKBH5 locus was strongly associated with MDD (uncorrected p=0.0008, OR=1.491,95%CI 1.179¨C1.887), with a global p value of 0.0036 after 10,000 permutations (Table 2). Genotypic association was detected for rs12936694 ( METTL3 locus showed a weak association with MDD (uncorrected ¦Ö2=12.26, df=2, p=0.0022). SNP rs17197156 in the p=0.0156, OR=1.2610, 95%CI 1.045¨C1.522), but such an association did not survive a correction with 10,000 permutations (global p=0.0790). There was no allelic association of rs9939609 in the FTO with MDD (¦Ö2=0.3422, p=0.5586). More...

Negative relationships between rs9939609 and other components at different levels (count: 0) Help
rs9939609 related genes (count: 0)