SNP Report

Basic Information

Name	rs4478239 dbSNP Ensembl
Location	Chrchr4:187270152(Forward)
Variant Alleles	C/A
Ancestral Allele	A
No. of Studies (Positive/Negative)	2 (0/2)

Positive relationship between rs4478239 and MDD (count: 0)

Relationships between rs4478239 and other components at different levels (count: 0)

Negative relationships between rs4478239 and MDD (count: 1)

Reference	Research Type	Statistical Result	Relation Description
Wray, 2010	patients and normal controls	P-value <10 -5	associated with MDD(P <10 -5) associated with MDD(P <10 -5)

Negative relationships between rs4478239 and other components at different levels (count: 1)

Name in Literature	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description
Name in Literature	Related Components
rs4478239		Stress(stressful life events)	environment	Shimasaki, 2014	Patients and nomal controls	P(ADD)=0.235;P(ADDxSLE)=0.521	Application of the quality control procedure showed that 45 ...... Application of the quality control procedure showed that 45 SNPs and 888 subjects were eligible for examination of the main effect of SNP and SNP 6 SLE interactions on the depressive state. In the logistic regression analysis, SLEs (experienced or not experienced) were associated with the depressive state for all SNPs (P=0.0042-4.0E-11). The effect size was relatively large, which indicated that the presence of SLEs has a high impact on developing the depressive state. Three SNPs showed significant associations as main effects on the depressive state ( full results are shown in S3 Table). The top finding was observed at rs7296288, which was selected on the basis of the BD GWAS results. More...

rs4478239 related genes (count: 0)