MK4MDD

Epigenetic Site Report

Basic Information
Epigenetic Site Name methylation-BDNF-22901293
Related Gene BDNF
Location chr11:0-0
Distance to Transcriptional Start Site(bp) 0
Relation to Gene promoter
No. of Studies (Positive/Negative) 1 (1/0) Help

Positive relationship between methylation-BDNF-22901293 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
methylation-BDNF-22901293 D'Addario C, 2013 patients and normal controls P-value <0.05 A signi?cant reduction of BDNF gene expression in MDD subjec...... A signi?cant reduction of BDNF gene expression in MDD subjects (.45+/-.10; p<.05, according to unpaired t test) versus controls(1.00+/-.21; Figure 1A)was observed. In addition, an increase of DNA methylation at BDNF gene promoter was observed in MDD patients, compared with control subjects (32.52% +/- 2.03% vs.24.04%+/- 2.08%; p <.05, according to unpaired t test; Figure 1B) More...

Positive relationships between methylation-BDNF-22901293 and other components at different levels (count: 0) Help
Data network of methylation-BDNF-22901293 in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationship between methylation-BDNF-22901293 and MDD (count: 0)
Negative relationships between methylation-BDNF-22901293 and other components at different levels (count: 0) Help