Comparison of patients with control subjects in the interfer......
Comparison of patients with control subjects in the interference condition revealed hyperactivity in left dorsolateral prefrontal cortex (DLPFC) in depressive patients, which correlated strongly with the Stroop interference. More...
In contrast to healthy subjects, left dorsolateral prefronta......
In contrast to healthy subjects, left dorsolateral prefrontal cortex (DLPFC) activity during emotional judgment was not parametrically modulated by negative emotional valence and was inversely modulated by positive emotional valence in MDD patients.More...
Source localization analyses at the time of maximal N450 act......
Source localization analyses at the time of maximal N450 activity revealed that MDD subjects had significantly reduced left dorsolateral prefrontal cortex (Brodmann area 10/46) activation to incongruent relative to congruent trials. More...
In the depressed group as a whole rCBF (regional cerebral bl......
In the depressed group as a whole rCBF (regional cerebral blood flow) was decreased in the left dorsolateral prefrontal cortex (P less than 0.05 Bonferroni-corrected for multiple comparisons). More...
Depressed subjects had significantly lower levels of glycero......
Depressed subjects had significantly lower levels of glycerophosphocholine plus phosphocholine (GPC + PC; or choline-containing compounds) and higher myo-inositol levels in the left DLPFC compared to healthy controls. IMore...
Patients showed significantly more activation of left dorsol......
Patients showed significantly more activation of left dorsolateral prefrontal cortex with highest cognitive load. More...
The non-remitting patients had reduced gray matter volume in......
The non-remitting patients had reduced gray matter volume in the left dorsolateral prefrontal cortex (DLPFC, BA 9). Voxel-based structural deficits in the left DLPFC may characterize a subgroup of people with recurrent MDD who respond poorly to antidepressants.More...
Relative to the controls, the participants with increased fa......
Relative to the controls, the participants with increased familial risk of depression (FH) had diminished responses in left dorsolateral prefrontal cortex (DLPFC) to the presentation of fearful facesMore...
The MDD subjects showed elevated left amygdala responses and......
The MDD subjects showed elevated left amygdala responses and reduced left dorsolateral prefrontal cortex (dlPFC) activation levels relative to HC subjects. More...
Positive relationships between left dorsolateral prefrontal cortex and other components at different levels (count: 0)
Positive relationship network of left dorsolateral prefrontal cortex in MK4MDD
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Note:
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Genetic/Epigenetic Locus
Protein and Other Molecule
Cell and Molecular Pathway
Neural System
Cognition and Behavior
Symptoms and Signs
Environment
MDD
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Negative relationships between left dorsolateral prefrontal cortex and MDD (count: 0)
Negative relationships between left dorsolateral prefrontal cortex and other components at different levels (count: 0)