Brain Morphology and Function Report

Name	dorsomedial prefrontal cortex (DMPFC)
Brain Morphology	Please reference to the description for Prefrontal cortex
No. of Studies (Positive/Negative)	6(6/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
dorsomedial prefrontal cortex	Bermpohl, 2009	patients and normal controls		Healthy individuals showed enhanced activation in the dorsom...... Healthy individuals showed enhanced activation in the dorsomedial prefrontal cortex and decreased activation in the dorsolateral prefrontal cortex during cued compared to uncued emotional picture perception. The group comparison revealed that these modulatory effects were significantly attenuated in depressed patients. More...
dorsomedial frontal region	Epstein, 2006	patients and normal controls		Relative to comparison subjects, depressed patients displaye...... Relative to comparison subjects, depressed patients displayed decreased activation to positive stimuli in a dorsomedial frontal region associated with processing of self-related stimuli. More...
dorsomedial prefrontal cortex (DMPFC)	Grimm, 2009	patients and normal controls		Neurally, patients with MDD showed significantly lower signa...... Neurally, patients with MDD showed significantly lower signal intensities in various subcortical and cortical midline regions like the dorsomedial prefrontal cortex (DMPFC), supragenual anterior cingulate cortex, precuneus, ventral striatum (VS), and the dorsomedial thalamus (DMT). More...
dorsomedial prefrontal cortex (DMPFC)	Amico, 2011	patients and high-risk people and normal controls		The HC-FHP(healthy controls with a positive family history f...... The HC-FHP(healthy controls with a positive family history for MDD) group had smaller right hippocampal and DLPFC grey matter volumes compared with the HC-FHN(healthy controls with no family history of any psychiatric disease) group, and even smaller right hippocampal volumes compared with patients with MDD. Patients with MDD exhibited smaller volumes in the ACC, DMPFC, DLPFC and the basal ganglia compared with healthy controls. More...
dorsomedial prefrontal cortex (DMPFC)	Salvadore, 2011	patients and normal controls		Relative to the HC(healthy controls) group the dMDD(currentl...... Relative to the HC(healthy controls) group the dMDD(currently-depressed participants) group had reduced gray matter in the dorsomedial (DMPFC). More...
dorsomedial PFC	Seidel, 2012	patients and normal controls		Applying a psycho-physiological interaction analysis, we obs...... Applying a psycho-physiological interaction analysis, we observed reduced coupling between a dorsomedial PFC seed region and limbic areas during self-serving attributions in patients compared to controls. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
dorsomedial PFC		Attribution and attitude(biased causal attribution)	cognition and behavior	Seidel, 2012	patients and normal controls		Applying a psycho-physiological interaction analysis, we obs...... Applying a psycho-physiological interaction analysis, we observed reduced coupling between a dorsomedial PFC seed region and limbic areas during self-serving attributions in patients compared to controls. More...
dorsomedial prefrontal cortex (DMPFC)		Depressed mood(depression)	symptoms	Grimm, 2009	patients and normal controls		Signal changes in the DMPFC correlated with depression sever...... Signal changes in the DMPFC correlated with depression severity and hopelessness. More...
dorsomedial prefrontal cortex (DMPFC)		Feelings of hopelessness, worthlessness, and guilt(hopelessness)	symptoms	Grimm, 2009	patients and normal controls		Signal changes in the DMPFC correlated with depression sever...... Signal changes in the DMPFC correlated with depression severity and hopelessness. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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3. The network is generated using Cytoscape Web