Protein Report

Protein Name	Thyrotropin subunit beta
UniPortKB	P01222
No. of Studies (Positive/Negative)	6 (6/0)
Type	Literature-origin

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
thyrotropin	Harbour, 1988	patients and normal controls		SEA- and TRH-treated cell cultures from depressed individual...... SEA- and TRH-treated cell cultures from depressed individuals had significantly fewer immunofluorescent positive cells, as well as significantly fewer and smaller plaques, than did similarly treated leukocytes from control subjects. More...
thyroid stimulating hormone	Sarandol, 2003	patients and normal controls		Thyroid Stimulating Hormone (TSH) responses to TRH(Thyroid R...... Thyroid Stimulating Hormone (TSH) responses to TRH(Thyroid Releasing Hormone test), maximal TSH responses, change in maximal TSH level were significantly lower in the patient group compared with the controls. More...
TSH	Brouwer, 2005	patients and normal controls	P-value < 0.001	The serum concentration of TSH was slightly higher in depres...... The serum concentration of TSH was slightly higher in depressed patients as compared with controls (P < 0.001) More...
thyrotropin	Duval, 2006	patients and normal controls		Compared with controls, patients showed lower responses to T...... Compared with controls, patients showed lower responses to TRH: 2300 h maximum increment in serum thyrotropin (TSH) level (p=0.006) and the difference between 2300 and 0800 h maximum increment in serum TSH values (p=0.0001). More...
TSH	Stipcevic, 2008	patients and normal controls		The results showed significantly lower T3 and TSH levels in ...... The results showed significantly lower T3 and TSH levels in patients compared to controls More...

Name in Literature	Related Components
	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
TSH		Sleep disturbances(sleep disturbances)	symptoms	Staner, 2003	patients only		Patients in cluster III (n=48) had the lowest TSH response t...... Patients in cluster III (n=48) had the lowest TSH response to TRH and the less marked sleep EEG alteration. Our results suggest that different biological dysfunctions could each underlie particular neuroendocrine and sleep EEG disturbances in major depression. More...

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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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Gene Symbol	Gene Name	Type	No. of Studies (Positive/Negative)	Add to Relationship Set
TSHB	thyroid stimulating hormone, beta	Protein mapped	0 (0/0)